Proteomics

Zichi, D., Eaton, B., Singer, B., & Gold, L. (2008). Proteomics and diagnostics: Let’s Get Specific, again. Current Opinion in Chemical Biology 2008, 12:78–85. Pubmed link is: http://www.ncbi.nlm.nih.gov/pubmed/18275862.

Carlson, Bob (2007) Aptamers: The New Frontier in Drug Development? Biotechnology Healthcare. April 2007: 31-36. Read the complete article or visit Biotechnolgy Healthcare's website.

(2007) Editorial: Proteomics' framework for success? Nature Methods. 4(1): 1-2. Link to abstract on Nature Methods site.

Gold, Larry (2006) A Personal Perspective: Aptamers after 15 Years. The Aptamer Handbook: Functional Oligonucleotides and Their Applications, Wiley-VCH Verlag GmbH, Klussman ed

Gander, T.R. & E.N. Brody (2005). Photoaptamer chips for clinical diagnostics. Expert Review of Molecular Diagnostics, 5(1):1-3.

Bock, C., Coleman, M., Collins, B., Davis, J., Foulds, G., Gold, L., Greef, C., Heil, Heilig, J.S., J., Hicke. B., Hurst, M.N., Husar, G.M., Miller, D., Ostroff, R., Petach, H., Schneider, D., Vant-Hull, B., Waugh, S., Weiss, A., Wilcox, S.K., & D. Zichi (2004). Photoaptamer arrays applied to multiplexed proteomic analysis. Proteomics, 4(3):609-618.

Gander, T.R., E.N. Brody, R.E. Mehler, J.S. Heilig, B.S. Singer, & L. Gold (2003). Driving forces in cancer diagnostics. MLO Med Lab Obs. 35(1): 11-12, 14-16, 20. Read the complete article

Petach, H. & L. Gold (2002). Dimensionality is the issue: use of photoaptamers in protein microarrays. Current Opinions in Biotechnology. 13(4):309-314.

Zichi, D., T. Koga, C. Greef, R. Ostroff, & H. Petach (2002). Photoaptamer technology: development of multiplexed microarray protein assays. Clinincal Chemistry. 48(10):1865-1868.

Brody, E., & L. Gold (2000). Aptamers as therapeutic and diagnostic agents. Reviews in Molecular Biotechnology, 74: 5-13.

Golden, M.C., B.D. Collins, M.C. Willis, & T.H. Koch (2000). Diagnostic potential of PhotoSELEX-evolved ssDNA aptamers. Journal of Biotechnology, 81: 167-178.

Brody, E.N., M.C. Willis, J.D. Smith, S. Jayasena, D. Zichi, & L. Gold (1999). The use of aptamers in large arrays for molecular diagnostics. Molecular Diagnostics, 4(4): 381-388.

Gold, L. (1999). Globular oligonucleotide screening via the SELEX process: Aptamers as high-affinity, high-specificity compounds for drug development and proteomic diagnostics. Combinatorial Chemistry and Technology: Principles, Methods and Applications, New York: Marcel Dekker, Inc., Chap. 16: 389-403.

Jayasena, S.D. (1999). Aptamers: An emerging class of molecules that rival antibodies in diagnostics. Clinical Chemistry, 45(9): 1628-1650.

Gold, L. (1995). Oligonucleotides as research, diagnostic, and therapeutic agents. J. Biol. Chem., 270(23): 13581-13584.

SELEX and PhotoSELEX

Davis, J. N. Janjic, B.E. Javornik, & D.A. Zichi (1996). Identifying consensus patterns and secondary structure in SELEX sequence sets. Methods in Enzymology, Chap. 18, 267: 302-314.

Fitzwater, T. & B. Polisky (1996). A SELEX primer. Methods in Enzymology, 267: 275-301 (Chapter 17).

Tuerk, C., & L. Gold (1990). Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science, 249: 505-510.

Other Applications

Davis, K., Y. Lin, B. Abrams, & S.D. Jayasena (1998). Staining of cell surface human CD4 with 2'-F-pyrimidine-containing RNA aptamers for flow cytometry. Nucleic Acids Research, 26(17): 3915-3924.

Drolet, D.W., L. Moon-McDermott, & T.S. Romig (1996). An enzyme-linked oligonucleotide assay. Nature Biotechnology, 14: 1021-1025.

Davis, K.A., B. Abrams, Y. Lin, & S.D. Jayasena (1996). Use of a high affinity DNA ligand in flow cytometry. Nucleic Acids Research, 24(4): 702-706.